Answer is YES.
When Rainier Plan to Mount Centori Outdoors RTT to his brand new 2020 4 runner, we discussed 2 different solutions, with bolts into skeleton or non-drill/full length supports on both sides.
Because it is a brand new car, we feel hard to destroy the roof with holes, in the end, it proved that the choice of this solution was correct, it is stable and strong!
If you have similar struggle or questions, welcome to discuss with us!